Sources said Mr Patnaik is scheduled to attend a meeting of the NITI Aayog and meet some Union Ministers during his five days stay in the national capital. He is scheduled to return to the state on April 26.
Mr Patnaik had been on a visit to Delhi earlier this month from April 7 to 11 and had attended the Inter-State Council meeting.
The Chief Minister's programme of visiting Delhi came a day after his meeting with his West Bengal counterpart Mamata Banerjee.
Earlier in March, Mr Patnaik had a discussion with JDU president and Bihar Chief Minister Nitish Kumar in Bhubaneswar.
JD(U) spokesman KC Tyagi had then told a local news channel that Nitish Kumar had a talk with Naveen Patnaik on the ensuing presidential elections and that efforts are on to field a candidate by non-BJP parties.