The Chief Minister will not have access to newspapers, televisions or any other media during the meditation course.
"The CM today left for Igatpuri. He will be attending a 10-day session of Vipassana," a government spokesperson said.
Deputy Chief Minister Manish Sisodia will take care of day-to-day government affairs in Mr Kejriwal's absence, he said.
In August last year too, Mr Kejriwal had gone to Himachal Pradesh's Dharamkot to attend a 10-day Vipassana session at a meditation centre.
This time, his meditation break comes after the hectic campaign for the Bawana bypolls, where his Aam Aadmi Party registered a win.
Mr Kejriwal had gone to Bengaluru earlier this year to undergo naturopathy treatment for high blood sugar, after months of campaigning for elections in Punjab and Goa.
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