The neural tube develops in the first month of pregnancy, medical professionals typically recommend women take a folic acid supplement during the first trimester of pregnancy. Continued supplementation may not be needed in the late stages of pregnancy and may actually increase the risk of allergies in offspring
For the study, the team of researchers measured systematic inflammation and tested skin reactions- markers of allergies, to the common allergens dust mites and egg whites in the lambs. The restricted group had higher levels of inflammation but no difference in skin reaction than the restricted supplement and control groups when exposed to dust mites.
According to the researchers, Patients should be counselled regarding the potential increase risks of progeny allergy of continuing folic acid supplementation for the entirety of pregnancy
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