A 42-member team of sleuths from the anti-graft unit was involved in the operation, a Lokayukta official said.
Documents pertaining to exports of alleged illegal iron ore and property were seized during the raids led by Lokayukta Deputy Superintendent of Police Sampath Kumar, the official said.
Mr Reddy is under probe by both Central Bureau of Investigation (CBI) and Lokayukta for alleged illegal mining deals linked to Oblapuram Mining Company and other cases.
Speaking to reporters in the midst of raids, BJP Lok Sabha member B Sriramulu, a one-time close associate of Mr Reddy, alleged that the raids were nothing but "political vendetta" by the Siddaramaiah government.
Mr Sriramulu alleged that the Congress government in the state was using Lokayukta with "political motives". He said he would soon file a complaint with CBI against some close associates of the Chief Minister and his son, alleging their links with illegal sand mining.
The once powerful Mr Reddy from the mine-rich Ballari district spent about 40 months in jail before being out on bail in January this year. He and his brother-in-law BV Srinivas Reddy, managing director of OMC, were arrested by CBI on September 5, 2011 from Ballari.
In the OMC case, the company is accused of changing mining lease boundary markings and indulging in illegal mining in the Ballari Reserve Forest area, spread over Ballari in Karnataka and Anantapur district of Andhra Pradesh.
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