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Am I on the right medication?
Question
I am a 31 years old male. I am a patient of cervical spondylosis with myelitis with HTN? Since last 6 months I am taking following drugs: 1. Dulane (Duloxetine)60 mgs (in the morning at 8 AM) 2. Atecard 50 mgs OD (at 1 PM) 3. Primox (Nortryptiline)(Initially 10 mgs OD and from the past 3 months 25 mgs OD) Below are the reports of the tests done this month: Hb - 15.6 g\dl PCV - 47.6% TLC - 8.10 thousand\mm3 RBC count - 4.61 mill\mm3 MCV - 103.2 FL MCH - 33.8 PG MCHC - 32.7 G\DL RDW - 14 % Platelet count - 320 THOU\MM3 Lymphocyte - 48.8% Monocytes -38.80 % Eosinophils - 6.50% Basophils - 1.10% ESR -12 MM IN 1 HR Blood picture: Predominantly normocytic normochromic, macrocytes few, mild lymphocytosis and eosinophilia. Serum creatinine - 1.30 MG\DL SGOT\AST - 67U\L SGPT - 152 U\L Serum potassium - 4.12 MEQ\L I am really worried about my raised ALT / AST / creatinine. I have stopped taking alcohol since the past 1 year. Do I continue with the above mentioned drugs? Will there be any side effects? Please tell me.
Expert Answer
S
Dr Shirish KumarAug 21, 2007
Haematologist,
WHO,
Geneva
WHO,
Geneva
It is likely that the altered liver enzymes are related to some of the medications that you are taking. The macrocytic red cell index (MCV:103 fl) may also be secondary to it. You need to discuss this with your physician as it is unwise to abruptly stop or change the dose of a drug. You may need to take vitamin B12 and/or folate for the macrocytosis.
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