The blast comes a week after ISIS claimed an attack on a training facility of the same agency, the National Directorate for Security, in Kabul that ended when the attackers were killed before causing significant casualties.
An official said the explosion occurred close to the agency's entrance.
Ismail Kawsi, a spokesman for the ministry of public health, said at least three dead and one wounded had been taken to city hospitals.
There was no immediate claim of responsibility.
(This story has not been edited by NDTV staff and is auto-generated from a syndicated feed.)