He added that only those government employees, who handled critical departments and essential services, would be on duty tomorrow.
"In the wake of the warnings issued by the IMD, those in Mumbai and surrounding areas are advised to stay home, unless there is an emergency," Mr Fadnavis said.
According to the MeT forecast, the Mumbai region, Southern Gujarat, North-Central Maharashtra and Goa may receive a heavy rainfall over the next 48 hours.
The IMD said the low pressure over these regions might be upgraded to a "depression", which would mean more rainfall.
The western coast of Maharashtra, including Mumbai, may receive up to 250 mm of rainfall in the next 48 hours.