The campaign, aimed at highlighting the Narendra Modi government's flagship cleanliness initiative 'Swachh Bharat Mission', was launched from Ishwari Ganj village near Kanpur. The president also made people take a pledge to keep their surroundings clean.
"Today we are fighting a different battle - battle against uncleanliness," he said. President Kovind said every person in the society was "rashtra nirmata" and invited NCC cadet Manish Dwivedi, who belongs to Kanpur, to the Rashtrapati Bhavan to meet him.
"The responsibility shown by people of Ishwariganj village to make their village open defecation free is laudable. I hope others will take a cue from this village," he said.
"We should make united efforts for cleanliness. It is not only the responsibility of the sanitation staff but all of us. Ensuring cleanliness will be the true tribute to Mahatma Gandhi," he said, adding diseases, including mental illness, can happen due to unclean atmosphere.
President Kovind also had a word of praise for those women who refused to marry into homes without any toilets. He also appreciated actors Amitabh Bachchan and Akshay Kumar for their support to the cause.
Uttar Pradesh Governor Ram Naik said it was more important for a household to have a toilet than a place of worship.
"Even if you do not have 'devghar' (place of worship), you must have toilets," he said.
Chief Minister Yogi Adityanath thanked the president for launching the campaign in his home state.
"The UP government has been associated with the Swacch Bharat Abhiyan and has constructed 10 lakh toilets so far. The target is to construct 78 lakh toilets by December 31, 2017 and make the state open defecation free (ODF) by October, 2018. I have written a letter to all the village heads for their support in this regard," he said.
The chief minister said four districts - Shamli, Bijnor, Hapur and Ghaziabad - had been made open defecation free, while by December 31, 2017, 30 districts would be brought under the ODF category, and by October next year, all the 75 districts in in the state will become open defecation free.
Speaking on the occasion, Union Drinking Water Sanitation Minister Uma Bharti noted the the main idea behind the campaign was to fulfil Mahatma Gandhi's dream of clean India and meet the prime minister's target of making the entire country open defecation free by 2019.
The government has identified special dates during the campaign period. September 17 has been reserved for the voluntary work and cleanliness and construction of toilets.
Vice President Venkaiah Naidu is scheduled to visit a village in Karnataka on September 17 and offer 'shramdaan' for toilet construction and general cleanliness.
On September 24, citizens at panchayat and municipal levels will take up voluntary work. On September 25, cleaning of public places, bus stands, hospitals will be done.
A special cleanliness drive is planned for 15 identified places on October 1.
The Doordarshan will also broadcast a world premiere of the film 'Toilet: Ek Prem Katha' on September 17.
September 17 also happens to be the birth date of Prime Minister Narendra Modi.
On October 2, Gandhi Jayanti, which is also the Swachh Bharat Diwas, awards for essays, short film and painting competitions will be given.