"This study supports the use of a yoga and coherent breathing intervention in major depressive disorder in people who are not on antidepressants and in those who have been on a stable dose of antidepressants and have not achieved a resolution of their symptoms," said Chris Streeter, associate professor at Boston University School of Medicine in the US.
Major depressive disorder (MDD) is common, recurrent, chronic and disabling. Due in part to its prevalence, depression is globally responsible for more years lost to disability than any other disease, researchers said.
Up to 40 per cent of individuals treated with antidepressant medications for MDD do not achieve full remission.
The study, published in the Journal of Alternative and Complementary Medicine, used lyengar yoga that has an emphasis on detail, precision and alignment in the performance of posture and breath control.
Individuals with MDD were randomised to the high dose group, three 90-minute classes a week along with home practice, or the low dose group, two 90-minute classes a week, plus home practice.
Although a greater number of subjects in the high dose group had less depressive symptoms, the researchers believe attending twice weekly classes (plus home practice) may constitute a less burdensome but still effective way to gain the mood benefits from the intervention.
According to Dr Streeter compared with mood altering medications, this intervention has the advantages of avoiding additional drug side effects and drug interactions.
"While most pharmacologic treatment for depression target monoamine systems, such as serotonin, dopamine and norepinephrine, this intervention targets the parasympathetic and gamma aminobutyric acid system and provides a new avenue for treatment," said Dr Streeter, who is also a psychiatrist at Boston Medical Centre.