- "I have my own experiences," said the actress
- "I find it really hard to sleep, hard to think," she added
- "(I feel) true disgust at the director who assaulted me," she said
Dozens of women have come forward to allege Mr Weinstein, a heavyweight Hollywood studio head, of sexual assault and in some cases rape.
Sharing her story, Ms Witherspoon said, "I have my own experiences that have come back to me very vividly and I find it really hard to sleep, hard to think, hard to communicate a lot of the feelings that I've been having about anxiety, honest, the guilt for not speaking up earlier."
"(I feel) true disgust at the director who assaulted me when I was 16-years-old and anger at the agents and the producers who made me feel that silence was a condition of my employment. And I wish that I could tell you that was an isolated incident in my career, but sadly it wasn't. I've had multiple experiences of harassment and sexual assault and I don't speak about them very often," she added.
Ms Witherspoon said reading about stories of other brave women convinced her to finally "speak up and speak up loudly because I actually felt less alone this week than I have ever felt in my entire career."
"I have just spoken to so many actresses and writers, particularly women, who have had similar experiences and many, of them have bravely gone public with their stories. That truth is very encouraging to me and everyone out there in the world because you can only heal by telling the truth," she said.
The actor-producer hoped that there would be a "new normal" where women have other women's back.
"It makes me so sad to talk about these issues, but I would be remiss not to," Ms Witherspoon concluded.
Her comments come after dozens of women have come forward to accuse Harvey Weinstein of sexual misconduct - including Cara Delevingne, Ashley Judd, Gywneth Paltrow and Angelina Jolie.
(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)