Twitter posts during the final two months of the 2016 election race shows that Ms Clinton was heavily criticised on social media compared to her rival Donald Trump.
Posts relating to WikiLeaks were the most common form of attack on social media for the Democratic candidate, who was also heavily criticised on Twitter over an FBI investigation into her use of a private email server, researchers said.
Researchers from the University of Edinburgh in the UK used computer analysis to study the top viral tweets each day between September 1 and November 8 last year. They found that there were three times as many posts attacking Ms Clinton than posts that were in her favour.
By contrast, viral tweets relating to Mr Trump were split equally in favour of and against his campaign.
Posts from Donald Trump's social media campaign and his supporters had a more positive tone than that of his rival, with effective reach for slogans, policy promises and campaigning for swing states.
Tweets backing Ms Clinton tended to compare her with her rival, and to attack Mr Trump rather than praise Ms Clinton.
Mr Trump was criticised for his performance in election debates more than his links to scandals such as the Access Hollywood tape.
Donald Trump supporters were more likely to share news reports from less credible sources, the study found.
In all researchers analysed almost 3,500 posts, which together were retweeted more than 25 million times. Tweets were labelled as being favourable to Donald Trump, Hillary Clinton, or neither. They used data from TweetElect.com, which collates the most retweeted posts related to the US election.