The episode had put the Central Michigan University campus into lockdown Friday morning -- trapping students in classrooms and dormitories until mid-afternoon -- while police conducted an expansive search for the 19-year-old suspected gunman.
James Eric Davis, described as a university student, was turned in by "an individual on a train passing through the north end of campus shortly after midnight", university officials said. Officers arrested him without incident.
The suspect is accused of killing his father, a police officer, and mother in a shooting inside a dormitory building in what a university police spokesman described as a "family-type domestic issue."
There were no other casualties.
The college campus in the city of Mount Pleasant in central Michigan was on lockdown hours after the 8:30 a.m. (1330 GMT) shooting, as federal, state and local law enforcement searched for Davis using helicopters and police dogs.
Heavily armed officers fanned out throughout the city, and residents and students were asked to stay inside and lock their doors.
University officials announced at 3:00 p.m. (2000 GMT) that students were finally being escorted out of buildings by police.
Suspect known to police
Davis, who was a resident of nearby Illinois state but attending college in Michigan, was known to law enforcement.
Police took him to a hospital the night before for what was believed to be a "drug-related type of incident -- an overdose or a bad reaction to drugs," campus police spokesman Larry Klaus told a news conference.
He was then released to hospital staff, Klaus said.
An Illinois state legislator identified Davis's victims as his parents, who lived in a Chicago suburb.
"The shooting at Central Michigan University today strikes close to home," tweeted the state representative, Emanuel Welch.
It was unclear what kind of weapon Davis used or how he acquired it.
The state of Michigan allows for the concealed carrying of a handgun with a permit, but Central Michigan University does not allow guns on campus.
The reaction to the shooting was swift Friday morning, with multiple alerts going out on social media and mobile phones within minutes of the incident.
With one day left before residence halls were scheduled to close for spring break, parents seeking out their children were told to go to a staging area at a nearby hotel.
The shooting came amid a renewed debate over pervasive gun violence and law enforcement's role in stopping potential shooters, which was sparked when a teenage gunman killed 17 people at a Parkland, Florida high school two weeks ago.
Accused gunman Nikolas Cruz had a history of run-ins with law enforcement, which have faced scrutiny over their failure to intervene despite multiple warnings.
Cruz used a semi-automatic assault rifle in his attack, leading students at Marjory Stoneman Douglas High School to make public appeals for change to permissive US gun laws.
President Donald Trump has called for training and arming some teachers, tougher background checks and a potential increase to the minimum age for rifle purchases.
But the powerful National Rifle Association gun lobby said that Trump was opposed to gun control after meeting with him on Thursday.
(This story has not been edited by NDTV staff and is auto-generated from a syndicated feed.)