The Syrian Observatory for Human Rights said 805 civilians including at least 178 children have been killed since Russia-backed regime forces launched an assault on the besieged enclave outside Damascus on February 18.
Russia suffered its own heavy losses on Tuesday as the defence ministry said a Russian transport plane crash landed at an airbase in western Syria, killing all 39 people on board.
At least 24 civilians were killed on Tuesday, according to the Observatory, a Britain-based monitor.
The relentless attacks prompted France and Britain to request an emergency meeting of the top UN body behind closed doors on Wednesday to discuss the ceasefire's failure to take hold.
Government troops have advanced rapidly across farmland in Eastern Ghouta in the past week and had wrested control of 40 percent of the enclave as of early Tuesday.
In the enclave's main town of Douma, air strikes have reduced homes to piles of rubble, an AFP correspondent reported.
Exhausted civil defence workers on Tuesday took advantage of a few hours of calm to dislodge the body of a resident, killed in bombardment several days ago, from a collapsed building.
Eastern Ghouta's around 400,000 residents have lived under government siege since 2013, facing severe shortages of food and medicines even before the latest offensive began.
Forty-six aid trucks entered the area on Monday for the first time since the offensive started, but had to cut short their deliveries and leave due to heavy bombardment.
Nearly half of the food carried on the convoy could not be delivered and Syrian authorities removed some medical and health supplies from the trucks, the United Nations said.
In a statement on Tuesday UN Secretary-General Antonio Guterres said he "calls on all parties to immediately allow safe and unimpeded access for further convoys to deliver critical supplies to hundreds of thousands of people in desperate need".
He urged all warring sides to allow aid trucks to return for a planned second delivery to Douma on Thursday.
Rebels Fire Mortars
Civilians in the area used the lull in air strikes to venture out from cellars to gather a few necessities from what was left of their homes.
Some gathered the pieces of furniture smashed in the raids to use as fuel or sell to their neighbours.
An AFP reporter in Hammuriyeh said air strikes were continuing to pummel the town on Tuesday.
The raids came after around 18 people suffered breathing difficulties in the town following a strike there late Monday, the Observatory reported.
It had no firm word on the cause.
The UN Human Rights Council on Monday ordered investigators to examine the latest violence in the enclave.
It condemned "the indiscriminate use of heavy weapons and aerial bombardments against civilians, and the alleged use of chemical weapons in Eastern Ghouta".
The area is the last opposition bastion on the Syrian capital's doorstep, and the regime is keen to retake it to secure Damascus.
Rebels there have fired waves of rockets and mortars onto eastern Damascus neighbourhoods.
On Tuesday, three civilians were killed and eight wounded in mortar fire on the neighbourhood of Jarmana, according to state news agency SANA.
'Corridor' Expanded To Rebels
Regime ally Russia last week announced a five-hour daily "humanitarian pause" in the region, during which it said it would guarantee safe passage to civilians wishing to flee the enclave.
No Syrian civilians are known to have used the "humanitarian corridor".
Russia's air force intervened in Syria in 2015 on behalf of President Bashar al-Assad, helping his troops retake key cities across the country.
It has been repeatedly accused of hitting civilians, and UN investigators on Tuesday said a Russian strike on a crowded Syrian market last year may amount to a "war crime".
The air strikes on a market in rebel-held Atareb in northern Syria last November 13 killed at least 84 people, including five children, and injured around 150 others, the UN Commission of Inquiry on human rights in Syria said in its latest report.
Moscow's defence ministry said on Tuesday that a Russian transport plane crashed on landing at the Hmeimim airbase, killing 33 passengers and six crew members all military personnel.
"The reason for the crash according to preliminary information could have been a technical fault," the ministry said, adding that the plane had not come under fire according to a report from the ground.
More than 340,000 people have been killed and millions displaced in Syria since the start of the civil war in 2011 with the brutal repression of anti-government protests.
Over the years, numerous rounds of UN-backed Syria peace talks have failed to stem the fighting.
In the latest attempt to end the seven-year war, the foreign ministers of regime allies Iran and Russia and rebel backer Turkey are to meet next week in Astana.
(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)