Maximino Rodriguez Palacios 'was shot and killed' outside a store as he arrived in his car at around noon (1700 GMT) with his wife who uses a wheelchair, the Colectivo Pericu news website said.
His wife was unharmed.
The state prosecutor's office confirmed the 71-year-old's murder 'from gunshot wounds', adding that investigators have obtained shell casings that will be analyzed in a lab.
Unknown attackers appeared to have used high-powered rifles in the attack, the website said.
According to early reports, the shooting occurred as Rodriguez was parking in a disabled parking spot and requested a wheelchair for his wife.
"We demand that the authorities clarify this and many other crimes that continue to go unpunished and have left families shattered by pain."
With its ruthless drug cartels, Mexico ranks third in the world for the number of journalists killed, after Syria and Afghanistan, according to media rights group Reporters Without Borders (RSF).
During his long career as a reporter and columnist, Rodriguez made "very strong, very critical" statements, RSF's Mexico representative Balbina Flores told AFP.
Three other journalists covering organized crime in Mexico have been killed since March 3 - in Chihuahua, Guerrero and Veracruz states, according to officials and media groups.