Watchman said that he had seen Kalyan Kumar and four other men in office.
Several crucial documents were destroyed at the office of the Department of Animal Husbandry in Telangana on Friday, the police said.
A complaint has been registered against the Officer on Special Duty (OSD) to former Minister of Animal Husbandry, Talasani Srinivas Yadav, for destroying the files and the security cameras at the office.
Police said a First Information report or FIR was registered against Kalyan Kumar and four others based on a complaint filed by the watchman at the office.
A window grill was removed to break into the office, it was learnt during the investigation.
The watchman told the police that he was on a routine check when he found the office of Kalyan Kumar ransacked and papers torn, dumped in huge sacks.
He said that he had seen Kalyan Kumar and four other men - Mohan, Elijah, Venkatesh and Prasanth - in the office corridor at the time of the incident. "I suspect Kalyan with the help of these four people might have taken away some key documents," the watchman said in his complaint.
"Some of the security cameras were also found broken and hanging on walls," officials said.
All the four men have been detained and further investigation is on, police said.
Police are also probing an incident when files from the office of the Education Department, were loaded on to an autorickshaw in an attempted theft.
The auto driver, however, managed to flee the spot after being caught by the office staff, officials said.