According to Xinhua, over 30 vehicles - including large trucks and buses - collided and several of them caught fire around 7.50 am on an expressway in Fuyang City.
Footage of the aftermath, posted on YouTube by CGTN, shows large clouds of smoke billowing from the site of the crash.
Firefighters walk past the burnt remains of vehicles that caught fire as the result of high-impact crash.
According to Astro Awani, a helicopter was flown in and doubled up as a "flying ambulance." Firefighters managed to rescue at least 17 people from the wreckage.
Emergency rescue teams are working with traffic police to re-open the expressway.
Click for more trending news