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What is atypical epitheliosis or gynaecomastia with atypia?
Question
The context is of gynaecomastia that my father has been diagnosed with in his right breast. The first FNAC report mentions atypical epitheliosis. A review of the slides by a second pathologist mentions gynaecomastia with focal area of atypia. What do atypical epitheliosis or gynaecomastia with focal area of atypia mean in layman's language? I would also like to know what is the implication of atypia - is it malignancy? Also, is it true that breast cancer in men is rare but it may be more threatening than breast cancer in women? What are the chances of it being cured? When there is a lump in the breast and one that is somewhat painful, is it an early or a late stage of the disease?
Expert Answer
Answered by: DoctorNDTV Team
If this is true unilateral gynaecomastia affecting the right breast alone in a 71 year old male it should be investigated adequately. The term Atypia itself does not mean malignancy but cannot be totally ignored either. It may mean just a small focal non-malignant change in an otherwise benign proliferative condition of gynaecomastia or may mean a more serious disease in another area. My suggestion is that the cytology already available may be reexamined by a dependable cytopathologist (for example, if the patient is in Delhi then I suggest Sir Ganga Ram Hospital Dept. of Pathology-Division of cytopatholgy) and if necessary a proper repeat FNAC done by them. The result from that would decide if surgery is to be done. At any rate, as I said earlier, if this change is confirmed to be only on one side a limited surgery may be necessary.
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