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Can brain surgery for tuberculoma lead to memory loss?
Question
My husband was operated for brain tuberculoma last year. He is having a short term memory problem since the surgery. Is this a side effect of any of the drugs he is taking viz. Rimatazid, Pyzina, Azetol. Does he need to take separate treatment to deal with this problem?
Expert Answer
C
Dr Chandra M GulhatiFeb 09, 2006
Editor, MIMS,
New Delhi
New Delhi
None of the medicines mentioned by you are likely to cause impairment of short term memory. Apparently the problem is due to surgery. With regard to anti-tubercular treatment, in 3-drugs therapy we give: rifampicin, isoniazid and ethambutol; in 4-drugs therapy we add pyrazinamide. Unfortunately pyrazinamide has a wide range of side effects particularly injury to liver; hence its use is reserved when 4 drugs are to be employed. The patient can be given a kit (such as CX-4 by Cadila) which contains rifampicin 450mg, isoniazid 300mg and ethambutol 800mg along with vitamin B-6 to prevent side effects.
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