He was administered the oath of office and oath of secrecy by Justice Girish Chandra Gupta, acting chief justice of Calcutta High Court at a formal swearing-in-ceremony held at Raj Niwas in Port Blair.
Mr Mukhi took over from Lt General A K Singh (Retd) who was appointed in July 2013.
At the function, Chief Secretary Anindo Majumdar read out the warrant of appointment.
Mr Mukhi had been a minister and Leader of Opposition in the Delhi Assembly in the past.
Mr Mukhi was a professor in Delhi University and has authored a book titled 'Company Law and Secretarial Practice'.
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