Here are 10 developments in this big story:
In the last 24 hours, Maharashtra, Andhra Pradesh, Karnataka, Tamil Nadu and Uttar Pradesh were the five states that recorded the highest number of Covid cases.
With over 4.6 lakh cases, Maharashtra is the worst-hit state by the outbreak. Maharahstra, Tamil Nadu, Karnataka, Andhra Pradesh and West Bengal reported the highest number of Covid-linked deaths since yesterday. Worldwide, the deaths linked to disease have crossed 700,000.
India, which is the third worst-affected by the novel coronavirus pandemic after the United States and Brazil, tested a record 6,64,949 samples in the last 24 hours, the government said. Over 2.21 crore samples have been tested so far by the country, which has a population of about 130 crore people. A patient can be tested more than once until recovery.
Eight Covid patients in Gujarat's Ahmedabad died this morning as fire broke out at the ICU ward of the hospital. Gujarat is among ten worst-affected states in India by the outbreak.
Several top politician leaders, including Union Home Minister Amit Shah, have contracted the virus in the last few days. Karnataka Chief Minister BS Yediruppa and Madhya Pradesh Chief Minister Shivraj Chouhan also tested positive recently. Mr Chouhan was discharged from the hospital yesterday.
On Wednesday, West Bengal logged the highest single-day surge in cases and deaths with 2,816 new cases were registered on Wednesday in the state while 61 COVID-19 patients died, taking the tally to over 83,000 cases.
India has reported more than nine lakh cases since July 17 when it crossed the 10-lakh mark. Last month, it recorded the biggest surge in cases and deaths.
The United states- epicentre of the pandemic - on Wednesday announced a new $1 billion investment in a COVID-19 vaccine being developed by Johnson & Johnson, guaranteeing 100 million doses.
Drugmakers will likely have tens of millions of doses of coronavirus vaccines in the early part of next year, Anthony Fauci, the top U.S infectious diseases official, said in a Reuters interview on Wednesday.
The World Health Organization warned Monday that there might never be a "silver bullet" for the new coronavirus, despite the rush to discover effective vaccines.