Two Republican women -- Senators Susan Collins and Lisa Murkowski -- along with John McCain joined Democrats in a dramatic thumbs-down vote that triggered the stunning collapse of Trump's health reforms.
But the president demanded that lawmakers revisit the hot-button issue, taunting them by saying that otherwise they are no more than "total quitters."
Unless the Republican Senators are total quitters, Repeal & Replace is not dead! Demand another vote before voting on any other bill!— Donald J. Trump (@realDonaldTrump) July 29, 2017
"Unless the Republican Senators are total quitters, Repeal & Replace is not dead! Demand another vote before voting on any other bill!" he wrote in a series of angry tweets over the space of several hours.
However, some lawmakers are also seeking a new path on health reform.
Republican Senators Lindsey Graham, Bill Cassidy and Dean Heller met with Trump on Friday on a plan that would task states -- rather than the federal government -- with crafting health care plans.
In an ominous warning, Trump appeared to threaten lawmakers that he would cut their health care benefits if they don't "quickly" approve a new bill.
"If a new HealthCare Bill is not approved quickly, BAILOUTS for Insurance Companies and BAILOUTS for Members of Congress will end very soon!" he wrote.
In an early morning tweet, he urged senators to end the legislative filibuster. Senate rules set a 60-vote minimum threshold to pass most legislation.
Yet the Republicans' Obamacare repeal measures only required a 51-vote majority in the Senate due to the process the chamber's leaders chose to push it through.
Republicans currently have 52 seats and Vice President Mike Pence casts a vote when there is a tie.
But the 60-vote requirement makes senators "look like fools," Trump said, adding that "8 Dems totally control the US Senate."
"Republicans in the Senate will NEVER win if they don't go to a 51 vote majority NOW. They look like fools and are just wasting time," he wrote.
There are growing signs, however, that Trump's threats against skeptical Republicans are losing potency.
Republicans not only killed efforts to dismantle Obamacare, but also joined Democrats in supporting a new sanctions regime against Russia.
The party rebellion is a deeply ominous sign for Trump, whose political brand is defined by his deal-making acumen and a take-no-prisoners approach to politics.
(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)