"Shortly after 4 pm (1400 GMT) police shot at a rampaging man at Berlin Cathedral," police said in a tweet.
"He was wounded in the leg."
The man's age and nationality were not known.
It was not immediately clear whether anyone else was hurt in the incident at Berlin's main Protestant cathedral, one of the city's top tourist attractions.
An AFP reporter said the entrances to the building were blocked off with red-and-white police tape and several officers with automatic weapons were patrolling the scene.
DPA news agency said some witnesses were taken away to receive psychological counselling.
(This story has not been edited by NDTV staff and is auto-generated from a syndicated feed.)
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