The strike targeted a vehicle suspected of carrying foreign militants in the North Waziristan tribal area, an Al Qaeda and Taliban stronghold that has been subject to frequent missile attacks, said the officials, speaking on condition of anonymity because they were not authorised to talk to the media.
The aircraft fired eight missiles at the vehicle as it drove near a roadside restaurant, killing at least 15 people, including foreign militants, said the officials. At least one civilian died when the missiles damaged the restaurant and a nearby home, they said.
It was unclear whether intelligence gleaned from the U.S. commando raid that killed bin Laden on Monday played a part in the drone strike.
Drone attacks are extremely unpopular in Pakistan, and the most recent attack could further increase tensions between the U.S. and Pakistan that have spiked in the wake of bin Laden's death.
The U.S. refuses to publicly acknowledge the covert CIA drone programme in Pakistan, but officials have said privately that the attacks have killed many senior Al Qaeda and Taliban commanders.
Pakistani officials regularly condemn the attacks as violations of the country's sovereignty. But many are believed to privately support the programme, and some of the drones are suspected of taking off from inside Pakistan.
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