Witnesses reported hearing gunfire and said the entire area around the Nasa Hablod hotel was sealed off by security forces to keep people away.
"A car loaded with explosives went off at the entrance of Nasa Hablod Hotel and there is gunfire," police official Ibrahim Mohamed told AFP, saying it looked like a coordinated attack.
"There was another minibus loaded with explosives which went off a nearby intersection," he said, confirming there were casualties but without giving an initial number.
The blasts occurred just two weeks after a huge truck bombing in the Somali capital which killed at least 358 people, making it the deadliest attack in the country's history.
An AFP correspondent at the scene also reported seeing two people lying on the ground but their condition was not immediately clear.
The Nasa Hablod is a popular hotel located in the north of the city.
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