A mineral supplement derived from seaweed may help people with knee arthritis cut down on painkillers. Researchers from America studied 22 adults with moderate to severe knee osteoarthritis (the wear-and-tear form of arthritis in which the cartilage cushioning the joints gradually wears down). The patients were randomly assigned to take either Aquamin F or inactive placebo capsules for 12 weeks. After the first two weeks of treatment, all patients were asked to cut their NSAID use in half for the next two weeks, and then stop the drugs completely for the rest of the study. It was found that those who took the mineral supplement from seaweed (Aquamin F) for 12 weeks were able to reduce their use of non-steroidal anti-inflammatory drugs - commonly known as NSAIDs - but still show improvements in walking ability and range of motion in the knee joint. In general Aquamin F patients performed better on tests of walking distance and knee joint range of motion after one month of treatment, despite their NSAID use being halved. However, the benefits did not continue once the patients stopped taking NSAIDs altogether. Six patients dropped out of the trial because of worsening pain - though five of them were in the placebo group. The findings indicate that Aquamin F cannot entirely replace NSAIDs as a treatment for knee arthritis. It's not fully clear why the seaweed supplement might aid arthritis symptoms. It contains a mix of trace minerals, with the main ingredients being calcium and magnesium. Some of those minerals have been shown to have anti-inflammatory effects in lab animals. For its part, calcium is known to boost bone mineral density, and there is some evidence that it may ease arthritis symptoms as well. Although these early results suggest that the seaweed supplement could reduce some patients' need for painkillers, additional research is needed to confirm these observations.
Nutrition Journal
March 2009