- Plane was flying to Orsk, a city in the Urals
- It crashed in the Ramensky district on the outskirts of Moscow
- There were 65 passengers and six crew on board
The Antonov An-148 plane operated by the domestic Saratov Airlines was flying to Orsk, a city in the Urals, and crashed in the Ramensky district on the outskirts of Moscow. Russian news agencies reported 65 passengers and six crew were on board and all were feared dead.
News agencies said witnesses in the village of Argunovo saw a burning plane falling from the sky.
A source from Russia's emergency services had told Interfax that the 71 people on board "had no chance" of survival.
President Vladimir Putin offered "his profound condolences to those who lost their relatives in the crash," his spokesman Dmitry Peskov said.
State television aired a video of the crash site, showing parts of the wreckage in the snow.
Russia has seen record high snowfall in recent days and visibility was reportedly poor.
The Russian-made plane was reportedly seven years old and bought by Saratov Airlines from another Russian airline a year ago.
Hard-to-reach crash site
Russian media reported that the emergency services were unable to reach the crash site by road and that rescue workers walked to the scene on foot. Emergency services said in a statement that more than 150 rescue workers were deployed to the site.
A source at Domodedovo, Moscow's second largest airport, told agencies that the plane disappeared from radars within two minutes of takeoff.
The Russian transport minister was on his way to the crash site, agencies reported. The transport ministry said several causes for the crash were being considered, including weather conditions and human error.
The governor of the Orenburg region, where the plane was flying to, told Russian media that "more than 60 people" on board the plane were from the region.
Prosecutors opened an investigation into Saratov Airlines following the crash. Russia's Investigative Committee will consider all possible causes, RIA Novosti news agency reported.
Saratov Airlines was founded in the 1930s and flies to 35 Russian cities. Its hub is Saratov Central Airport in southern Russia.
Local media website Ural56.ru in the Orenburg region showed footage of distressed relatives at Orsk airport, where the plane was due to land.
Andrei Odintsov, the mayor of the city of Orsk, told Russian state television that six psychologists and four ambulances with medics are working with the relatives in the small airport.
Orsk is the second biggest city in the Orenburg region, near Russia's border with Kazakhstan.
Russia has suffered numerous plane crashes, with airlines often operating ageing aircraft in dangerous flying conditions.
A light aircraft crashed in November in Russia's far east, killing six people on board.
In December 2016 a military plane carrying Russia's famed Red Army Choir crashed after taking off from the Black Sea resort of Sochi, killing all 92 people on board.
The choir had been due to give a concert to Russian troops operating in Syria.
Pilot error was blamed for that crash.
In March 2016, all 62 passengers died when a FlyDubai jet crashed in bad weather during an aborted landing at Rostov-on-Don airport.