Los Angeles Fire Department spokesman David Ortiz says more than 250 firefighters were battling the blaze early Monday morning.
The Los Angeles Times reports that the fire could be seen for miles.
The fire was burning a building planned to be a tall residential structure.
Ortiz says he didn't think anyone was living or working there.
Ortiz says that the cause and extent of the fire are not yet known. There were no immediate reports of injuries.
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