A city planning committee approved 90 units in Gilo and another 150 in Ramat Shlomo, Turjeman said, the latest in a series of moves to enhance Jewish presence in the contested Israeli-annexed Palestinian sector of the city.
Turjeman noted the committee also approved 44 units for Palestinians in their neighbourhood of Beit Hanina.
The Ramat Shlomo units are part of plans announced in 2010 to build 1,600 settler homes in Ramat Shlomo, an ultra-Orthodox Jewish neighbourhood in east Jerusalem.
The 2010 announcement came as then US vice president Joe Biden was visiting Israel, provoking fierce US opposition and souring relations with Washington for months.
Wednesday's approvals were granted weeks after the same committee voted on an expansion creating the largest Israeli settlement within a Palestinian neighbourhood in the city.
Jerusalem's status is ultra-sensitive and central to the Israeli-Palestinian conflict.
Earlier this month, the Israeli ministers were set to approve a bill absorbing major Israeli settlements currently in the occupied West Bank into Jerusalem by enlarging the city limits.
Its opponents argue that it is a step towards full unilateral annexation of the West Bank settlements affected -- a move that would be sure to spark international outrage.
The White House has been seeking ways to restart long-stalled Israeli-Palestinian peace talks, and a US official said the bill would "distract the principals from focusing on the advancement of peace negotiations."
Israeli NGO Ir Amim, which opposes settlement construction, said approving new settler homes distances the possibility of a two-state solution to the conflict.
"Jerusalem residents deserve to live in a safe and thriving city, which will only happen once there's a fair agreement that recognises the Israeli and Palestinian ownership of the city," the organisation's Aviv Tatarsky told AFP.
"Instead of advancing such an agreement, Israeli authorities continue with the same familiar unilateral moves that only distance it," he said.
Israel occupied the West Bank and east Jerusalem in the Six-Day War of 1967. It later annexed east Jerusalem in a move never recognised by the international community.
It sees the entire city as its indivisible capital, while the Palestinians want the eastern sector as the capital of their future state.
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