Macron received a total of 20,753,797 votes, compared with 10,644,118 for Marine Le Pen, the ministry announced the day after the landmark election.
The abstention rate was 25.44 per cent, the highest since the presidential election in 1969.
The interior ministry on Sunday reported a record number of blank and invalid ballots, accounting for nine per cent of all registered voters, compared with two per cent in the first round.
Together with the abstention rate, that means that one in three voters declined to choose between the two candidates.
The abstention rate was 22.23 per cent for during the first round of the election on April 23, making it the first time since the 1969 election that turnout was lower in the second round than in the first.
Casting a blank ballot -- traditionally used by disgruntled French voters as a protest vote -- usually increases in the second round.
But this year it quadrupled, thanks in part to an unprecedented situation of neither the two mainstream left-leaning or right-leaning parties making it to the run-off.
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