Tensions between the United States and Iran have escalated sharply after Iran's Defence Minister issued a strong warning in response to remarks by US President Donald Trump. Tehran said it would respond "powerfully" to any attack and warned that all US bases in the region, along with countries facilitating Washington's actions, would be considered legitimate targets. The statement comes after President Trump urged Iranians to continue protesting and "take over" state institutions, while announcing the cancellation of all meetings with Iranian officials, raising fears of a wider regional confrontation.