NASA’s Artemis II astronauts fired their engines and blazed toward the moon Thursday night, breaking free of the chains that have trapped humanity in shallow laps around Earth in the decades since Apollo. The so-called translunar ignition came 25 hours after liftoff, putting the three Americans and a Canadian on course for a lunar fly-around early next week. Their Orion capsule bolted out of orbit around Earth right on cue and chased after the moon nearly 250,000 miles (400,000 kilometers) away. Speaking live from on board the Orion, alongside his crewmates pilot Victor Glover, mission specialist Christina Koch and CSA (Canadian Space Agency) astronaut Jeremy Hansen, Commander Reid Wiseman acknowledged the effort behind the mission.