Islam Karimov, who had ruled Uzbekistan since 1989, had been hospitalised last Saturday.
Uzbek President Islam Karimov has died after suffering a stroke at the age of 78, three diplomatic sources told Reuters today, leaving no obvious successor to take over.
The Uzbek government did not immediately confirm the reports. Earlier today it said the health of Karimov, who has been in hospital since last Saturday, had sharply deteriorated.
"Yes, he has died," one of the diplomatic sources said when asked about Karimov's condition.
Long criticised by the West and human rights groups for his authoritarian style of leadership, Karimov had ruled Uzbekistan since 1989, first as the head of the local Communist Party and then as president of the newly independent republic from 1991.
Karimov did not designate a successor and analysts say the transition of power is likely to be decided behind closed doors by a small group of senior officials and family members.
If they fail to agree on a compromise, however, open confrontation could destabilise the nation of 32 million that has become a target for Islamist militants.
Uzbekistan is a major cotton exporter and is also rich in gold and natural gas.
A hint at who is going to succeed Karimov may come with the government's announcement of his death - which one source said was expected later today - and whoever it names to head the commission in charge of organising the funeral.
The latter appeared likely to take part in Karimov's hometown of Samarkand where his mother and two brothers are buried. Municipal authorities there mobilised public workers to clean the central streets late on Thursday.
A source in the government of neighbouring Kazakhstan told Reuters on Friday that Kazakh President Nursultan Nazarbayev planned to cut short his visit to China and travel to Uzbekistan on Saturday.
Among potential successors are Prime Minister Shavkat Mirziyoyev and his deputy Rustam Azimov. Security service chief Rustam Inoyatov and Karimov's younger daughter Lola Karimova-Tillyaeva are also players who could become kingmakers.
According to the constitution, Nigmatilla Yuldoshev, the chairman of the upper house of parliament, is supposed to take over after Karimov's death, and elections must take place within three months.
However, analysts do not consider Yuldoshev a serious player. His erstwhile counterpart in Turkmenistan, who was also supposed to become interim leader after the death of authoritarian president Saparmurat Niyazov in 2006, was quickly detained and thus eliminated from the line of succession.
© Thomson Reuters 2016