The frontpage captioned "Never mind Brexit, who won Legs-it!", appeared on Twitter on Monday night, the Guardian reported.
Inside the paper there was more ogling at the female leaders, with a headline reading: "Finest weapons at their command? Those pins!"
A column by Sarah Vine referred to Sturgeon's legs as "altogether more flirty, tantalisingly crossed... a direct attempt at seduction".
Among the first to criticise were Labour MPs Harriet Harman and Yvette Cooper.
Journalist Alastair Campbell, labelled the paper "utter scum" and urged anyone who spotted a copy of the Mail to rip it up, the Guardian reported.
The former Labour leader Ed Miliband tweeted: "The 1950s called and asked for their headline back".
The front page, which referenced difficult talks between the leaders in Glasgow over Brexit, looked slightly different in Scotland, where it used the same photograph but with a headline that read: "Oh so frosty! Secrets of Nicola and PM's talk-in".