The F-16 fighter plane destroyed an area where members of the ultra-hardline Sunni group were operating, it said in a statement.
ISIS, which once occupied a third of Iraq's territory, has been largely defeated in the country but still poses a threat along its border with Syria.
The Iraqi air force has carried out several air strikes against ISIS in Syria since last year, with the approval of the Syrian government of President Bashar al-Assad and the U.S.-led coalition fighting ISIS.
Prime Minister Haider al-Abadi declared final victory over ISIS in December but it still operates from pockets along the border with Syria and has continued to carry out ambushes, assassinations and bombings across Iraq.
ISIS has resorted to guerrilla tactics since it abandoned its goal of holding territory and creating a self-sufficient caliphate that straddles Iraq and Syria.
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