The businessman-turned-president made the announcement side by side with the Taiwanese tech giant's CEO Terry Gou, as he tried to show his "America First" economic rhetoric is making a difference.
Trump said the plant -- which will make LCD panels -- will create at least 3,000 jobs in the midwestern state, and was quick to stress he played a role in making the deal happen.
"If I didn't get elected, he would not be spending $10 billion," Trump said, thanking Gou for his "faith and confidence in the future of the American economy."
Trump allies said Gou had spotted an abandoned factory and suggested it be used, and Trump personally met Gou in April to push the deal forward.
Trump has made returning manufacturing jobs to America's heartland a key plank of his domestic policy.
The investment is a double win for Trump, burnishing his reputation as a job creator and putting those jobs in a key battleground state, which he won in 2016 by a single percentage point.
The investment is also a victory for top Congressional Republican Paul Ryan, as the massive investment in his home state is tangible evidence that difficult ties with Trump can bring results.
"One thing we know about this president is how committed he is to reviving American manufacturing and bringing jobs home, this right here shows actual results, getting it done," Ryan said at the White House event.
The White House would not say what tax incentives were offered to entice the company, but local media reported a package of around $3 billion in tax breaks.
Foxconn, also known as Hon Hai, has been mulling moving to the US since at least the beginning of this year, hoping to have better control over distribution networks.
The firm is the world's largest contract electronics maker and is best-known for assembling products for international brands such as Apple and Sony.
It employs around a million workers at its factories across China and has operations in more than 10 countries.
In the US, it has a plant in Virginia for packaging and engineering which employs over 400 people.
It has also announced a $40 million investment in a facility in Pennsylvania to build precision tools and develop a robotics program.
(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)