S-500 Defence System | S-500 vs S-400: How Do The Two Missile Systems Differ From Each Other? Crucially, unlike the S-400 deal, the S-500 is being pitched as a co-production agreement that will see an Indian partner team up with Russia's Almaz Antey to manufacture parts of the missile locally. The S-400 has a range of up to 400 km, while the S-500 stretches to roughly 500-600 km. The S-400 intercepts targets up to 30 km high, while the S-500 intercepts targets up to 180-200 km in the near-space layer. The S-500 is a major level up in terms of what it can track and shoot down too. The S-400 counters aircraft, drones and cruise missiles while S-500 counters all of those plus long-range ballistic missiles and is said to be effective against hypersonic glide vehicles too, though this remains in the realm of claim