Democrat Annie Andrews has won a projected victory in South Carolina’s US Senate race, defeating Republican Darline Graham in a major upset in the traditionally conservative state. Andrews, a paediatrician, is set to become the first woman from South Carolina elected to the US Senate and the first Democrat to win a Senate seat in the state since 1998, according to media projections. Addressing cheering supporters in Charleston, Andrews said the seat did not belong to one family, one party or Washington, but to the people of South Carolina. Her victory comes as Democrats seek to regain control of Congress in the 2026 US midterm elections. President Donald Trump had backed Graham, the sister of the late Senator Lindsey Graham, in the race.