Historic high-level talks between the United States and Iran in Islamabad ended without a breakthrough after nearly 21 hours of intense negotiations. Led by JD Vance and Abbas Araghchi, the talks marked the highest-level engagement since the 2015 nuclear deal. However, deep divisions over Iran's nuclear programme, sanctions relief, control of the Strait of Hormuz, and broader geopolitical demands led to a collapse. Despite Pakistan positioning itself as a diplomatic host, the negotiations ended in stalemate, underscoring persistent mistrust and widening gaps between the two sides.