Iranian missile strikes hit southern Israel’s cities of Arad and Dimona late Saturday, causing widespread damage and leaving dozens injured. Several buildings were destroyed, a bus was badly damaged, and rescue teams rushed to multiple impact sites across the Negev region. Israeli air defenses reportedly failed to intercept some of the incoming missiles, raising concerns over vulnerabilities as sirens sent residents scrambling for safety. The strikes come hours after Iran’s Natanz nuclear facility was targeted, marking a sharp escalation in the ongoing conflict. Israeli Prime Minister Benjamin Netanyahu described it as a “very difficult evening,” as casualties rise and tensions deepen in the fourth week of the Iran-Israel war.