Vigorous Exercise May Weaken Immune System
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14 June 2025
Firefighters underwent rigorous training, carrying 40 pounds of gear over hilly terrain for 45 minutes
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Scientists analyzed over 4,700 molecules from each firefighter to understand intense exercise effects
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Researchers found hundreds of molecular changes, indicating tissue damage and repair efforts underway rapidly
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The oral microbiome changed, showing increased vigilance for bacterial invaders after intense exercise sessions
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Signaling molecules for inflammation and fighting viral infections decreased after vigorous exercise sessions
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Less inflammation helps improve respiration and blood flow, but increases vulnerability to viral infections
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Findings provide a molecular basis for increased vulnerability to respiratory infections after strenuous workouts noted
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