Ms Lodhi told reporters that such proposals of nuclear restraint should be first implemented by India before Pakistan does it.
"Pakistan's nuclear programme cannot be limited," Ms Lodhi said at the joint press conference with Foreign Secretary Aizaz Chaudhry.
"The world should first put an end to nuclear activities undertaken by India."
The remarks came a day after US Secretary of State John Kerry urged Prime Minister Nawaz Sharif to limit Pakistan's atomic programme.
"Kerry also stressed the need for restraint in nuclear weapon programmes. The secretary praised Pakistan for hosting the Afghan refugees for over 40 years and highlighted the importance of continued respect for humanitarian principles."
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