In sealing Mr Trump's first major legislative victory since he took office in January, Republicans steamrolled opposition from Democrats to pass a bill that slashes taxes for corporations and the wealthy while giving mixed, temporary tax relief to middle-class Americans.
The House approved the measure by 224-201, passing it for the second time in two days after a procedural foul-up forced another vote on Wednesday. The Republican-led Senate had passed it 51-48 in the early hours of Wednesday.
"We are making America great again," Mr Trump said, echoing his campaign slogan at a White House celebration with Republican lawmakers. "Ultimately what does it mean? It means jobs, jobs, jobs, jobs."
Mr Trump, who emphasized a tax cut for middle-class Americans during his 2016 campaign, said at an earlier Cabinet meeting that lowering the corporate tax rate to 21 per cent from 35 per cent was "probably the biggest factor in this plan".
It was uncertain when the bill would be signed. White House economic adviser Gary Cohn said the timing depended on whether automatic spending cuts triggered by the legislation could be waived.
The administration expects the waiver to be included in a spending resolution Congress will pass later this week, a White House official told reporters. Mr Cohn told Fox News Channel on Wednesday night that Trump could sign the bill as soon as Friday if the resolution was passed by then.
"If not, most likely we'll sign it in the first week of the new year," Mr Cohn said.
In addition to cutting the US corporate income tax rate, the debt-financed legislation gives other business owners a new 20 per cent deduction on business income and reshapes how the government taxes multinational corporations along the lines that the country's largest businesses have recommended for years.
Wall Street's main indices were little changed on Wednesday, taking a breather after a month-long rally ahead of the long-anticipated tax vote. The S&P 500 has climbed about 4.5 per cent since mid-November, led by a rally in sectors such as transport, banks and others that are expected to benefit the most from lower taxes.
Under the bill, millions of Americans would stop itemizing deductions, putting tax breaks that incentivize home ownership and charitable donations out of their reach, but also making tax returns somewhat simpler and shorter.
The bill keeps the existing number of tax brackets but adjusts many of the rates and income levels for each one. The top tax rate for high earners is reduced. The estate tax on inheritances is changed so far fewer people will pay.
Once signed, taxpayers likely would see the first changes to their paycheck tax withholdings in February. Most households will not see the full effect of the tax plan on their income until they file their 2018 taxes in early 2019.
"We have essentially repealed Obamacare and we'll come up with something that will be much better," Mr Trump said.
Democrats were united in opposition to the tax legislation, calling it a giveaway to the wealthy that will widen the income gap between rich and poor, while adding $1.5 trillion over the next decade to the $20 trillion national debt. Mr Trump promised during the campaign that he would eliminate the national debt.
"Today the Republicans take their victory lap for successfully pillaging the American middle class to benefit the powerful and the privileged," House Democratic leader Nancy Pelosi said.
Opinion polls show the tax bill is unpopular with the public and Democrats promised to make Republicans pay for their vote during next year's congressional elections, when all 435 House seats and 34 of the 100 Senate seats will be up for grabs.
"Republicans will rue the day they passed this bill," Senate Democratic leader Chuck Schumer told reporters. "We are going to continue hammering away about why this bill is so unpopular."
US House Speaker Paul Ryan defended the bill, saying support would grow for after it passes and Americans felt relief. "I think minds are going to change," Ryan said on ABC's "Good Morning America" television program.
A few Republicans, a party once defined by fiscal hawkishness, have protested the deficit spending encompassed in the bill. But most voted for it anyway, saying it would help businesses and individuals while boosting an already expanding economy they see as not growing fast enough.
In the House, 12 Republicans voted against the tax bill. All but one, Walter Jones of North Carolina, were from the high-tax states of New York, New Jersey and California, which will be hit by the bill's cap on deductions for state and local taxes.
Despite Trump administration promises that the tax overhaul would focus on the middle class and not cut taxes for the rich, the nonpartisan Tax Policy Center, a think tank in Washington, estimated middle-income households would see an average tax cut of $900 next year under the bill, while the wealthiest 1 percent of Americans would see an average cut of $51,000.
The House was forced to vote again after the Senate parliamentarian ruled three minor provisions violated arcane Senate rules. To proceed, the Senate deleted the three provisions and then approved the bill.
Since the House and Senate must approve the same legislation before Mr Trump can sign it into law, the Senate's vote sent the bill back to the House.