The global wealth intelligence and prospecting company said Mr Pudur, the owner and president of software firm Celframe, topped the list with a personal fortune of $4 billion.
Mr Pudur, a 37-year-old native of Chennai, founded Celframe in 1998 after graduating from university, and the software firm now produces the world's second most popular word processor after Microsoft.
He also has assets tied up in diversified businesses in the fields of mining and real estate, Wealth-X said.
Mr Pudur is followed by Zhou Yahui of China at the second place with a net worth of $2.2 billion.
The Chinese dominated the list with six entrepreneurs in the top 10, while Japan had three. Nine of the self-made billionaires on the Wealth-X top 10 list amassed fortunes from the technology sector.
The youngest entrepreneur on the list is 32-year-old Leo Chen, who is the chairman and CEO of Jumei International Holding, one of China's largest online cosmetics retailers.
Chen became a billionaire after Jumei's listing at the New York Stock Exchange in May 2014, the report said.
Others on the list include Yao Jinbo of China with a fortune of $2.2 billion ranked 4th on the list, followed by He Zhitao (5th, net worth of $2 billion), Naruatsu Baba (6th, $1.6 billion), Kenji Kasahara (7th, $1.5 billion), Yusaku Maezawa (8th, $1.3 billion), Pang Shengdong (9th, $1.2 billion).
Get Breaking news, live coverage, and Latest News from India and around the world on NDTV.com. Catch all the Live TV action on NDTV 24x7 and NDTV India. Like us on Facebook or follow us on Twitter and Instagram for latest news and live news updates.