While Mr Naidu was speaking, the Congress MP interjected. Mr Naidu called her bewakoof (stupid) for disrupting his speech.
Ms Thakur, upset over the comments, broke down in tears, and was seen outside Parliament being comforted by Rashtriya Janata Dal (RJD) chief Lalu Prasad and senior Congress leader Renuka Chowdhary.
Her party, the Congress lodged a protest wanting an apology from Mr Naidu. Lalu Prasad also joined that demand.
"I went to the lobby and saw our Congress colleague Madam Prabha Thakur was feeling bad I met her personally I understood her feelings I have no disrespect to anybody, If she's hurt by my this thing I express regret, I always hold everybody in high esteem," Mr Naidu apologised in the House.
Ms Thakur currently represents Rajasthan in the Rajya Sabha. She is also the president of the All India Mahila Congress. She is a renowned Hindi poetess and social worker too.