Speaking on behalf of the victims, with Headley present inside the court room, a teary-eyed Kia Scherr, who lost her husband and daughter in the attack told a federal court that Headley must be made to bear the consequences of what he did.
"I feel that the magnitude of the killing that took place (in Mumbai), David Headley has no right to live. He must bear the consequences of (what he did?)... this would be morale outrage if David Headley got only 35 years," said Kia Scherr.
Mrs Scherr is the widow of Alan Scher and mother of Naomi Scher, who were shot dead during the Mumbai terror attack.
Weeping in the court room as she described the events of the day, Mrs Scherr told Headley: "I do not know you. I know you only from the testimony you gave in this courtroom. I have no understanding of how you choose this path. Your path is not my concern and justice is not my concern".
The Pakistani-American Lashkar-e-Toiba terrorist was sentenced to 35 years in jail by the court later.
Earlier, Mrs Scher read out from Andreina Varagona, who had witnessed the attack and the killing of her husband and daughter.
"Two gunmen came running into the packed restaurant, bullets flying. I remember hearing screams and saw all of us sitting there, frozen with fear. 'Everyone get under the table now', I shouted on instinct," read Ms Varagona's testimony.
Ms Varagona was dining with the Scherrs, describing what happened on that fateful day.
"I had no idea who the gunmen were or why we under attack. All six of us dived down but Naomi was so scared - she just kept screaming and screaming. Her dad, Alan, was desperately trying to calm her. Shots were ringing out as the gunmen peppered the restaurant with fire. 'We have to play dead', I said".
"But as I reached up to grab Alan's neck, I suddenly felt the warm spray of blood on my face and in my hair... Naomi's screams had stopped too and I saw her lying lifeless besides him. They'd both been shot dead," Mrs Scher said quoting Ms Varagona.
Lashkar-e-Toiba terrorists, who entered Mumbai through the sea route from Pakistan, gunned down Alan Scherr and his 13-year-old daughter, Naomi at the Oberoi hotel.
Mrs Scherr was a university professor and worked with the Synchronicity Foundation, a spiritual organisation. Mrs Scherr and Naomi lived in Virginia, where Naomi was a high-achieving student who was home-schooled.
The Scherrs traveled to India on a spiritual pilgrimage in November 2008 with approximately 20 other people.
They were killed while eating in the first-floor cafe of the Oberoi Hotel and four other members of their group were injured.